Lancet Oncology Tuesday, September 11, 2018

Trabectedin is an alkylating drug with a unique mechanism of action causing single-strand and double-strand DNA breaks that activate DNA damage-response pathways. Based on our...

Lancet Oncology Tuesday, August 30, 2016

Background: Cancer of unknown primary ranks in the top ten cancer presentations and has an extremely poor prognosis. Identification of the primary tumour and development of a tailored site-...

Cancer Discovery Monday, June 20, 2016

A patient with metastatic BRAF-mutated colorectal cancer initially responded to combined EGFR and BRAF inhibition with panitumumab plus vemurafenib. Pre-existing cells with increased MET gene copy...

Sci Transl Med Monday, February 29, 2016

The anti-epidermal growth factor receptor (EGFR) antibodies cetuximab and panitumumab are used to treat RAS wild-type colorectal cancers (CRCs), but their efficacy is limited by the...

Nature Wednesday, September 30, 2015

Nature. 2015 Sep 30. doi: 10.1038/nature14969. [Epub ahead of print]
Bertotti A, Papp E, Jones S, Adleff V, Anagnostou V, Lupo B, Sausen M, Phallen J, Hruban CA, Tokheim C, Niknafs N,...

Cancer Res. Friday, July 3, 2015

Cancer Res. 2015 Jul 3. pii: canres.0356.2015. [Epub ahead of print]
Hultberg A, Morello V, Huyghe L, De Jonge N, Blanchetot C, Hanssens V, de Boeck G, Silence K, Festjens E, Heukers R, Roux...

J Mol Med (Berl). Friday, July 3, 2015

J Mol Med (Berl). 2015 Jul 3. [Epub ahead of print]
Errichiello E, Balsamo A, Cerni M, Venesio T.
Mitochondrial DNA alterations have been widely reported in different...

Ann Oncol. Thursday, June 25, 2015

Ann Oncol. 2015 Jun 25. pii: mdv272. [Epub ahead of print]
Barault L, Amatu A, Bleeker FE, Moutinho C, Falcomatà C, Fiano V, Cassingena A, Siravegna G, Milione M, Cassoni P, De Braud F, Rudà...

Clin Cancer Res. Friday, June 12, 2015

Clin Cancer Res. 2015 Jun 12. pii: clincanres.0848.2015. [Epub ahead of print]
Bertotti A, Sassi F.
Monoclonal antibodies targeting the EGF receptor (EGFR) tyrosine...

Mol Oncol. Friday, June 5, 2015

Vigna E, Chiriaco C, Cignetto S, Fontani L, Basilico C, Petronzelli F, Comoglio PM.
Mol Oncol. 2015 Jun 5. pii: S1574-7891(15)00122-2. doi: 10.1016/j.molonc.2015.05.007. [Epub ahead of print...



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